ncRNA name | Cx43 siRNA |
ncRNA Category | siRNA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | rat retinal endothelial cells (RRECs) |
Methods | siRNA transfection, Western blot, Co-immunoprecipitation, immunostaining |
Expression pattern | associated |
Functional description | Cells transfected with Cx43 siRNA and grown in N medium showed significant downregulation in occludin and ZO-1 expression, and exhibited increased cell monolayer permeability. |
PubMed ID | 24008412 |
Year | 2013 |
Title | Effects of high glucose-induced Cx43 downregulation on occludin and ZO-1 expression and tight junction barrier function in retinal endothelial cells. |
Drug-related ncRNA | NO |
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